Nancy Drew from the Nancy Drew Series 

Greasers and Socs from The Outsiders

A Handmaid from The Handmaid's Tale 

Frankenstein's Monster from Frankenstein

Miss Clavel, Madeline, and Co. from the Madeline Series 

The Pigeon from Don't Let the Pigeon Drive the Bus!

Ms. Frizzle and the Magic School Bus from The Magic School Bus Series

Lisbeth Salander from the Millennium Series

Waldo from Where's Waldo?

Curious George and The Man with the Yellow Hat

Rhett Butler and Scarlett O'Hara from Gone with the Wind

Robin Hood from The Adventures of Robin Hood

Hunter S. Thompson 

Sherlock Holmes (and Watson) from the Sherlock Holmes Series

Alanna the Lionness from The Song of the Lionness

Elizabeth Bennet and Fitzwilliam Darcy from Pride and Prejudice 

Dorian Gray (and His Portrait) from The Picture of Dorian Gray

Sam Vimes from the Discworld series

Mary Poppins and Bert from the Mary Poppins Series 

Hogwarts Faculty from the Harry Potter Series 

Miss Marple from the Miss Marple Mystery Series

Charlotte the Spider from Charlotte's Web

50 Shades of Grey

Mouse from If You Give a Mouse a Cookie

Westley, Buttercup, and Co. from The Princess Bride